Structure of PDB 3b86 Chain A Binding Site BS01

Receptor Information
>3b86 Chain A (length=124) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MTMEQFLTSLDMIRSGCAPKFKLKTEDLDRLRVGDFNFPPSQDLMCYTKC
VSLMAGSVNKKGEFNAPKALAQLPHLVPPEMMEMSRKSVEACRDTHKQFK
ESCERVYQTAKCFSENADGQFMWP
Ligand information
Ligand IDEOH
InChIInChI=1S/C2H6O/c1-2-3/h3H,2H2,1H3
InChIKeyLFQSCWFLJHTTHZ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.352
OpenEye OEToolkits 1.7.0		CCO
ACDLabs 11.02OCC
FormulaC2 H6 O
NameETHANOL
ChEMBLCHEMBL545
DrugBankDB00898
ZINC
PDB chain3b86 Chain A Residue 500 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3b86 The role of multiple hydrogen-bonding groups in specific alcohol binding sites in proteins: insights from structural studies of LUSH.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		S52 S57 T109
Binding residue
(residue number reindexed from 1)		S52 S57 T109
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005549 odorant binding
GO:0005550 pheromone binding
GO:0035274 diphenyl phthalate binding
GO:0035275 dibutyl phthalate binding
GO:0035276 ethanol binding
Biological Process
GO:0007608 sensory perception of smell
GO:0007619 courtship behavior
GO:0019236 response to pheromone
GO:0042048 olfactory behavior
GO:0045471 response to ethanol
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3b86, PDBe:3b86, PDBj:3b86
PDBsum3b86
PubMed18234222
UniProtO02372|OB76A_DROME General odorant-binding protein lush (Gene Name=lush)

[Back to BioLiP]