Structure of PDB 3b71 Chain A Binding Site BS01

Receptor Information
>3b71 Chain A (length=134) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLL
ATVDETIPLLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQE
YKKQMLTAAHALAVDAKNLLDVIDQARLKMLGQT
Ligand information
Receptor-Ligand Complex Structure
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PDB3b71 Structural basis for the interaction between focal adhesion kinase and CD4.
Resolution2.82 Å
Binding residue
(original residue number in PDB)
I936 H1025 K1032
Binding residue
(residue number reindexed from 1)
I21 H110 K117
Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Gene Ontology
Molecular Function
GO:0004713 protein tyrosine kinase activity
Biological Process
GO:0006468 protein phosphorylation
GO:0007172 signal complex assembly
Cellular Component
GO:0005925 focal adhesion

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:3b71, PDBe:3b71, PDBj:3b71
PDBsum3b71
PubMed18078954
UniProtQ05397|FAK1_HUMAN Focal adhesion kinase 1 (Gene Name=PTK2)

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