Structure of PDB 3auz Chain A Binding Site BS01

Receptor Information
>3auz Chain A (length=316) Species: 2190 (Methanocaldococcus jannaschii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RGSHMMFVHIADNHLGYRQYNLDDREKDIYDSFKLCIKKILEIKPDVVLH
SGDLFNDLRPPVKALRIAMQAFKKLHENNIKVYIVAGNHEMPRRLGEESP
LALLKDYVKILDGKDVINVNGEEIFICGTYYHKKSKREEMLDKLKNFESE
AKNYKKKILMLHQGINPYIPLDYELEHFDLPKFSYYALGHIHKRILERFN
DGILAYSGSTEIIYRNEYEDYKKEGKGFYLVDFSGNDLDISDIEKIDIEC
REFVEVNIKDKKSFNEAVNKIERCKNKPVVFGKIKREFKPWFDTLKDKIL
INKAIIVDDEFIDMPD
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain3auz Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3auz Crystal Structure of the Mre11-Rad50-ATP S Complex: Understanding the Interplay between Mre11 and Rad50
Resolution3.206 Å
Binding residue
(original residue number in PDB)		D8 H10 D49 H188
Binding residue
(residue number reindexed from 1)		D12 H14 D53 H192
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
Biological Process
GO:0006302 double-strand break repair

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3auz, PDBe:3auz, PDBj:3auz
PDBsum3auz
PubMed
UniProtQ58719|MRE11_METJA DNA double-strand break repair protein Mre11 (Gene Name=mre11)

[Back to BioLiP]