Structure of PDB 3ask Chain A Binding Site BS01
Receptor Information
>3ask Chain A (length=213) Species:
9606
(Homo sapiens) [
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SLYKVNEYVDARDTNMGAWFEAQVVRVTRKAEEDVIYHVKYDDYPENGVV
QMNSRDVRARARTIIKWQDLEVGQVVMLNYNPDNPKERGFWYDAEISRKR
ETRTARELYANVVLGDDSLNDCRIIFVDEVFKIERPGEGSPMVDNPMRRK
SGPSCKHCKDDVNRLCRVCACHLCGGRQDKQLMCDECDMAFHIYCPPLSS
VPSEDEWYCPECR
Ligand information
>3ask Chain P (length=10) Species:
9606
(Homo sapiens) [
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ARTKQTARKS
Receptor-Ligand Complex Structure
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PDB
3ask
Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF1
Resolution
2.904 Å
Binding residue
(original residue number in PDB)
F152 Y188 D190 Y191 E193 Q330 L331 M332 D334 D337 E355 D356
Binding residue
(residue number reindexed from 1)
F20 Y41 D43 Y44 E46 Q181 L182 M183 D185 D188 E204 D205
Enzymatic activity
Enzyme Commision number
2.3.2.27
: RING-type E3 ubiquitin transferase.
External links
PDB
RCSB:3ask
,
PDBe:3ask
,
PDBj:3ask
PDBsum
3ask
PubMed
22837395
UniProt
Q96T88
|UHRF1_HUMAN E3 ubiquitin-protein ligase UHRF1 (Gene Name=UHRF1)
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