Structure of PDB 3apa Chain A Binding Site BS01

Receptor Information
>3apa Chain A (length=138) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RSSSYSGEYGSGGGKRFSHSGNQLDGPITALRVRVNTYYIVGLQVRYGKV
WSDYVGGRNGDLEEIFLHPGESVIQVSGKYKWYLKKLVFVTDKGRYLSFG
KDSGTSFNAVPLHPNTVLRFISGRSGSLIDAIGLHWDV
Ligand information
Ligand IDGOL
InChIInChI=1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2
InChIKeyPEDCQBHIVMGVHV-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.0C(C(CO)O)O
ACDLabs 12.01
CACTVS 3.370		OCC(O)CO
FormulaC3 H8 O3
NameGLYCEROL;
GLYCERIN;
PROPANE-1,2,3-TRIOL
ChEMBLCHEMBL692
DrugBankDB09462
ZINCZINC000000895048
PDB chain3apa Chain A Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3apa Crystal structures of human secretory proteins ZG16p and ZG16b reveal a Jacalin-related beta-prism fold
Resolution1.65 Å
Binding residue
(original residue number in PDB)		G35 G147 S148 L149 D151
Binding residue
(residue number reindexed from 1)		G14 G126 S127 L128 D130
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0030246 carbohydrate binding
GO:0042834 peptidoglycan binding
Biological Process
GO:0015031 protein transport
GO:0050830 defense response to Gram-positive bacterium
GO:0052373 suppression of symbiont entry into host
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005794 Golgi apparatus
GO:0005796 Golgi lumen
GO:0031410 cytoplasmic vesicle
GO:0042589 zymogen granule membrane
GO:0062023 collagen-containing extracellular matrix
GO:0070701 mucus layer

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3apa, PDBe:3apa, PDBj:3apa
PDBsum3apa
PubMed21110947
UniProtO60844|ZG16_HUMAN Zymogen granule membrane protein 16 (Gene Name=ZG16)

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