Structure of PDB 3al3 Chain A Binding Site BS01
Receptor Information
>3al3 Chain A (length=218) Species:
9606
(Homo sapiens) [
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KQYIFQLSSLNPQERIDYCHLIEKLGGLVIEKQCFDPTCTHIVVGHPLRN
EKYLASVAAGKWVLHRSYLEACRTAGHFVQEEDYEWGSSSILDVLTGINV
QQRRLALAAMRWRKKIQQRQESGIVEGAFSGWKVILHVDQSREAGFKRLL
QSGGAKVLPGHSVPLFKEATHLFSDLGVNIAEAAAQNVYCLRTEYIADYL
MQESPPHVENYCLPEAIS
Ligand information
>3al3 Chain B (length=10) Species:
9606
(Homo sapiens) [
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SIYFTPELYD
Receptor-Ligand Complex Structure
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PDB
3al3
Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint control
Resolution
2.15 Å
Binding residue
(original residue number in PDB)
S1273 S1274 L1275 P1277 R1280 H1311 L1313 R1314 N1315 K1317 R1407 F1411 T1466 E1467 A1470
Binding residue
(residue number reindexed from 1)
S8 S9 L10 P12 R15 H46 L48 R49 N50 K52 R142 F146 T193 E194 A197
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3al3
,
PDBe:3al3
,
PDBj:3al3
PDBsum
3al3
PubMed
21127055
UniProt
Q92547
|TOPB1_HUMAN DNA topoisomerase 2-binding protein 1 (Gene Name=TOPBP1)
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