Structure of PDB 3af6 Chain A Binding Site BS01

Receptor Information
>3af6 Chain A (length=637) Species: 70601 (Pyrococcus horikoshii OT3) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TQVDQILRDIRAVVNQMVPKEAKITEIEFEGPELVIYVKNPEELIKDLAK
VLKKRISVRPDPEVLLPPEEAEKLIFEIVPKEAEITNIAFDPSVGEVLIE
AKKPGLVIGKNGETLRLITQKVKWAPKVVRTPPLQSQTIYSIRQILQTES
KDRRKFLRQVGRNIYRKPEYKSRWIRITGLGGFREVGRSALLVQTDESFV
LVDFGVNVAMLNDPYKAFPHFDAPEFQYVLREGLLDAIIITHAHLDHCGM
LPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQSNGQDPLYRPRDIK
EVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLHNIAI
TGDFKFIPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIE
VIHNTIKRGGKVLIPAMAVGRAQEVMMVLEEYARIGGIEVPIYLDGMIWE
ATAIHTAYPEYLSRRLREQIFKEGYNPFLSEIFHPVANSRERQDIIDSNE
PAIIIASSGMLVGGPSVEYFKQLAPDPKNSIIFVSYQAEGTLGRQVQSGI
REIPMVGEEGRTEVIKVNMEVHTIDGFSGHADRRELMNYVAKVRPRPERI
ITVHGEPQKCLDLATSIHRKFGISTRAPNNLDTIRLR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3af6 Crystal structure of an archaeal cleavage and polyadenylation specificity factor subunit from Pyrococcus horikoshii
Resolution2.6 Å
Binding residue
(original residue number in PDB)		I59 K60 A63 K67 K68 R69 I70 V328 R329 D330 R336 H354 G358 N361 P384 R385
Binding residue
(residue number reindexed from 1)		I45 K46 A49 K53 K54 R55 I56 V314 R315 D316 R322 H340 G344 N347 P370 R371
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0004521 RNA endonuclease activity
GO:0004527 exonuclease activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006353 DNA-templated transcription termination

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Molecular Function
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Biological Process
External links
PDB RCSB:3af6, PDBe:3af6, PDBj:3af6
PDBsum3af6
PubMed20544974
UniProtO50112|FTTA_PYRHO Transcription termination factor FttA (Gene Name=fttA)

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