Structure of PDB 3a6n Chain A Binding Site BS01

Receptor Information
>3a6n Chain A (length=97) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLMREIAQDFKTDLRFQSS
AVMALQEACESYLVGLFEDTNLCVIHAKRVTIMPKDIQLARRIRGER
Ligand information
>3a6n Chain I (length=145) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcaatatccacctgcagattctaccaaaagtgtatttggaaactgctcc
atcaaaaggcatgttcagctgaattcagctgaacatgccttttgatggag
cagtttccaaatacacttttggtagaatctgcaggtggatattga
Receptor-Ligand Complex Structure
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PDB3a6n Structural basis of instability of the nucleosome containing a testis-specific histone variant, human H3T
Resolution2.7 Å
Binding residue
(original residue number in PDB)		Y41 R42 P43 T45 R63 R72 F84 Q85 S86 R116 V117 T118
Binding residue
(residue number reindexed from 1)		Y4 R5 P6 T8 R26 R35 F47 Q48 S49 R79 V80 T81
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
Cellular Component
GO:0000781 chromosome, telomeric region
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0070062 extracellular exosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3a6n, PDBe:3a6n, PDBj:3a6n
PDBsum3a6n
PubMed20498094
UniProtQ16695|H31T_HUMAN Histone H3.1t (Gene Name=H3-4)

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