Structure of PDB 2zxn Chain A Binding Site BS01

Receptor Information
>2zxn Chain A (length=240) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLSEEQQHIIAILLDAHHKTYDPTYADFRDFRPPVRMSPLSMLPHLADLV
SYSIQKVIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLRSNQSFTMDDM
SWDCGSQDYKYDVTDVSKAGHTLELIEPLIKFQVGLKKLNLHEEEHVLLM
AICIVSPDRPGVQDAKLVEAIQDRLSNTLQTYIRCRHPPPGSHQLYAKMI
QKLADLRSLNEEHSKQYRSLSFQPENSMKLTPLVLEVFGN
Ligand information
Receptor-Ligand Complex Structure
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PDB2zxn A New Class of Vitamin D Analogues that Induce Structural Rearrangement of the Ligand-Binding Pocket of the Receptor
Resolution2.1 Å
Binding residue
(original residue number in PDB)		I238 K242 S252 Q255 I256 L259 K260 P412 E416
Binding residue
(residue number reindexed from 1)		I58 K62 S72 Q75 I76 L79 K80 P232 E236
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:2zxn, PDBe:2zxn, PDBj:2zxn
PDBsum2zxn
PubMed19193059
UniProtP13053|VDR_RAT Vitamin D3 receptor (Gene Name=Vdr)

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