Structure of PDB 2znl Chain A Binding Site BS01

Receptor Information
>2znl Chain A (length=421) Species: 211044 (Influenza A virus (A/Puerto Rico/8/1934(H1N1))) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IEPFLKTTPRPLRLPNGPPCSQRSKFLLMDALKLSIEDPSHEGEGIPLYD
AIKCMRTFFGWKEPNVVKPHEKGINPNYLLSWKQVLAELQDIIPKTKNMK
KTSQLKWALGPELRSLASWIQNEFNKACELTDSSWIELDEIGEDVAPIEH
IASMRRNYFTSEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMIS
KCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKW
EKYCVLEIGDMLSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESM
IEAESSVKEKDMTKEFFENKSETWPIGESPKGVEESSIGKVCRTLLAKSV
FNSLYASPQLEGFSAESRKLLLIVQALRDNLEPGTFDLGGLYEAIEECLI
NDPWVLLNASWFNSFLTHALS
Ligand information
>2znl Chain B (length=15) Species: 211044 (Influenza A virus (A/Puerto Rico/8/1934(H1N1))) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
MDVNPTLLFLKVPAQ
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2znl The structural basis for an essential subunit interaction in influenza virus RNA polymerase
Resolution2.3 Å
Binding residue
(original residue number in PDB)		Q408 N412 M595 E617 T618 W619 P620 I621 G622 E623 L666 Q670 R673 W706 F710
Binding residue
(residue number reindexed from 1)		Q121 N125 M300 E322 T323 W324 P325 I326 G327 E328 L371 Q375 R378 W411 F415
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Biological Process
GO:0039694 viral RNA genome replication

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Molecular Function
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Biological Process
External links
PDB RCSB:2znl, PDBe:2znl, PDBj:2znl
PDBsum2znl
PubMed18660801
UniProtP03433|PA_I34A1 Polymerase acidic protein (Gene Name=PA)

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