Structure of PDB 2zke Chain A Binding Site BS01
Receptor Information
>2zke Chain A (length=210) Species:
10090
(Mus musculus) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
SGMACVGRTTECTIVPANHFGPIPGVPVGTMWRFRVQVSESGVHRPHVAG
IHGRSNDGAYSLVLAGGYEDDVDNGNYFTYTGSGGRDLSGNKRTAGQSSD
QKLTNNNRALALNCHSPINEKGAEAEDWRQGKPVRVVRNMKGGKHSKYAP
AEGNRYDGIYKVVKYWPERGKSGFLVWRYLLRRDDTEPEPWTREGKDRTR
QLGLTMQYPE
Ligand information
>2zke Chain C (length=12) [
Search DNA sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
ctaccggattgc
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
2zke
Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism
Resolution
2.6 Å
Binding residue
(original residue number in PDB)
A407 C408 G410 R411 H450 H455 G456 R457 S458 N494 R496 N508
Binding residue
(residue number reindexed from 1)
A4 C5 G7 R8 H47 H52 G53 R54 S55 N91 R93 N105
Enzymatic activity
Enzyme Commision number
2.3.2.27
: RING-type E3 ubiquitin transferase.
External links
PDB
RCSB:2zke
,
PDBe:2zke
,
PDBj:2zke
PDBsum
2zke
PubMed
18772891
UniProt
Q8VDF2
|UHRF1_MOUSE E3 ubiquitin-protein ligase UHRF1 (Gene Name=Uhrf1)
[
Back to BioLiP
]
