Structure of PDB 2zkd Chain A Binding Site BS01
Receptor Information
>2zkd Chain A (length=210) Species:
10090
(Mus musculus) [
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SGMACVGRTTECTIVPANHFGPIPGVPVGTMWRFRVQVSESGVHRPHVAG
IHGRSNDGAYSLVLAGGYEDDVDNGNYFTYTGSGGRDLSGNKRTAGQSSD
QKLTNNNRALALNCHSPINEKGAEAEDWRQGKPVRVVRNMKGGKHSKYAP
AEGNRYDGIYKVVKYWPERGKSGFLVWRYLLRRDDTEPEPWTREGKDRTR
QLGLTMQYPE
Ligand information
>2zkd Chain C (length=12) [
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ctaccggattgc
Receptor-Ligand Complex Structure
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PDB
2zkd
Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism
Resolution
1.6 Å
Binding residue
(original residue number in PDB)
A407 C408 G410 R411 R448 H450 V451 H455 G456 R457 S458 N494 R496 N508
Binding residue
(residue number reindexed from 1)
A4 C5 G7 R8 R45 H47 V48 H52 G53 R54 S55 N91 R93 N105
Enzymatic activity
Enzyme Commision number
2.3.2.27
: RING-type E3 ubiquitin transferase.
External links
PDB
RCSB:2zkd
,
PDBe:2zkd
,
PDBj:2zkd
PDBsum
2zkd
PubMed
18772891
UniProt
Q8VDF2
|UHRF1_MOUSE E3 ubiquitin-protein ligase UHRF1 (Gene Name=Uhrf1)
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