Structure of PDB 2zhb Chain A Binding Site BS01

Receptor Information
>2zhb Chain A (length=436) Species: 2234 (Archaeoglobus fulgidus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KVEEILEKALELVIPDEEEVRKGREAEEELRRRLDELGVEYVFVGSYARN
TWLKGSLEIDVFLLFPEEFSKEELRERGLEIGKAVLDSYEIRYAEHPYVH
GVVKGVEVDVVPCYKLKEPKNIKSAVDRTPFHHKWLEGRIKGKENEVRLL
KGFLKANGIYGAEYKVRGFSGYLCELLIVFYGSFLETVKNARRWTRRTVI
DVAKGEVRKGEEFFVVDPVDEKRNVAANLSLDNLARFVHLCREFMEAPSL
GFFKPKHPLEIEPERLRKIVEERGTAVFAVKFRKPDIVDDNLYPQLERAS
RKIFEFLERENFMPLRSAFKASEEFCYLLFECQIKEISRVFRRMGPQFED
ERNVKKFLSRNRAFRPFIENGRWWAFEMRKFTTPEEGVRSYASTHWHTLG
KNVGESIREYFEIISGEKLFKEPVTAELCEMMGVKD
Ligand information
>2zhb Chain B (length=34) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggcccggggcgguucgauuccgcccugggccauc
<<<<<<<<<<<<.......>>>>>>>>>>>>...
Receptor-Ligand Complex Structure
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PDB2zhb Molecular basis for maintenance of fidelity during the CCA-adding reaction by a CCA-adding enzyme
Resolution3.05 Å
Binding residue
(original residue number in PDB)		D61 F63 A95 E96 Y99 D110 V127 A163 E164 Y165 A228 N229 D291 N292 P295 Q296 R299 R302 R310 G346 P347 N354 K357 F358 R361 R363 Y392 H396 H398 G401 K402
Binding residue
(residue number reindexed from 1)		D60 F62 A94 E95 Y98 D109 V126 A162 E163 Y164 A227 N228 D290 N291 P294 Q295 R298 R301 R309 G345 P346 N353 K356 F357 R360 R362 Y391 H395 H397 G400 K401
Enzymatic activity
Enzyme Commision number 2.7.7.72: CCA tRNA nucleotidyltransferase.
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0000287 magnesium ion binding
GO:0003723 RNA binding
GO:0004810 CCA tRNA nucleotidyltransferase activity
GO:0005524 ATP binding
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
GO:0160016 CCACCA tRNA nucleotidyltransferase activity
Biological Process
GO:0001680 tRNA 3'-terminal CCA addition
GO:0008033 tRNA processing
GO:0031123 RNA 3'-end processing
GO:0042245 RNA repair
GO:0106354 tRNA surveillance

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Molecular Function
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Biological Process
External links
PDB RCSB:2zhb, PDBe:2zhb, PDBj:2zhb
PDBsum2zhb
PubMed18583961
UniProtO28126|CCA_ARCFU CCA-adding enzyme (Gene Name=cca)

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