Structure of PDB 2z3p Chain A Binding Site BS01

Receptor Information
>2z3p Chain A (length=232) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQRGIFPWFS
PGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEG
CASDREEGTWITRGVVEAYHRLHELGHAHSIEVWREDELVGGMYGVAQGT
LFCGESMFSRMENASKTALLVFCEEFIGHGGKLIDCQVLNDHTASLGACE
IPRRDYLNYLNQMRLGRLPNNFWVPRCLFSPQ
Ligand information
Ligand IDLEU
InChIInChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1
InChIKeyROHFNLRQFUQHCH-YFKPBYRVSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0CC(C)C[C@@H](C(=O)O)N
CACTVS 3.341CC(C)C[C@H](N)C(O)=O
OpenEye OEToolkits 1.5.0CC(C)CC(C(=O)O)N
ACDLabs 10.04O=C(O)C(N)CC(C)C
CACTVS 3.341CC(C)C[CH](N)C(O)=O
FormulaC6 H13 N O2
NameLEUCINE
ChEMBLCHEMBL291962
DrugBankDB00149
ZINCZINC000003645145
PDB chain2z3p Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2z3p Protein-based peptide-bond formation by aminoacyl-tRNA protein transferase
Resolution2.5 Å
Binding residue
(original residue number in PDB)		G155 E156 C187 Q188
Binding residue
(residue number reindexed from 1)		G154 E155 C186 Q187
Annotation score1
Enzymatic activity
Enzyme Commision number 2.3.2.6: lysine/arginine leucyltransferase.
Gene Ontology
Molecular Function
GO:0008914 leucyl-tRNA--protein transferase activity
GO:0016746 acyltransferase activity
GO:0016755 aminoacyltransferase activity
Biological Process
GO:0030163 protein catabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2z3p, PDBe:2z3p, PDBj:2z3p
PDBsum2z3p
PubMed17891155
UniProtP0A8P1|LFTR_ECOLI Leucyl/phenylalanyl-tRNA--protein transferase (Gene Name=aat)

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