Structure of PDB 2z3k Chain A Binding Site BS01

Receptor Information
>2z3k Chain A (length=231) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQRGIFPWFS
PGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEG
CASDREEGTWITRGVVEAYHRLHELGHAHSIEVWREDELVGGMYGVAQGT
LFCGESMFSRMENASKTALLVFCEEFIGHGGKLIDCQVLNDHTASLGACE
IPRRDYLNYLNQMRLGRLPNNFWVPRCLFSP
Ligand information
Ligand IDXYA
InChIInChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6+,7-,10-/m1/s1
InChIKeyOIRDTQYFTABQOQ-GAWUUDPSSA-N
SMILES
SoftwareSMILES
CACTVS 3.341Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO)[C@H](O)[C@H]3O
CACTVS 3.341Nc1ncnc2n(cnc12)[CH]3O[CH](CO)[CH](O)[CH]3O
ACDLabs 10.04n2c1c(ncnc1n(c2)C3OC(C(O)C3O)CO)N
OpenEye OEToolkits 1.5.0c1nc(c2c(n1)n(cn2)[C@H]3[C@@H]([C@H]([C@H](O3)CO)O)O)N
OpenEye OEToolkits 1.5.0c1nc(c2c(n1)n(cn2)C3C(C(C(O3)CO)O)O)N
FormulaC10 H13 N5 O4
Name2-(6-AMINO-OCTAHYDRO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL;
9-BETA-D-XYLOFURANOSYL-ADENINE
ChEMBLCHEMBL1236872
DrugBankDB03528
ZINCZINC000003978049
PDB chain2z3k Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2z3k Protein-based peptide-bond formation by aminoacyl-tRNA protein transferase
Resolution2.85 Å
Binding residue
(original residue number in PDB)		E108 S157 N191 H193
Binding residue
(residue number reindexed from 1)		E107 S156 N190 H192
Annotation score1
Enzymatic activity
Enzyme Commision number 2.3.2.6: lysine/arginine leucyltransferase.
Gene Ontology
Molecular Function
GO:0008914 leucyl-tRNA--protein transferase activity
GO:0016746 acyltransferase activity
GO:0016755 aminoacyltransferase activity
Biological Process
GO:0030163 protein catabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2z3k, PDBe:2z3k, PDBj:2z3k
PDBsum2z3k
PubMed17891155
UniProtP0A8P1|LFTR_ECOLI Leucyl/phenylalanyl-tRNA--protein transferase (Gene Name=aat)

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