Structure of PDB 2yx4 Chain A Binding Site BS01

Receptor Information

>2yx4 Chain A (length=150) Species: 111955 (Sulfurisphaera tokodaii)

MDEIDLRILKILQYNAKYSLDEIAREIRIPKSTLSYRIKKLEKDGVIKGY
YAYINPASLNLDYIVITSVKAKYGKNYHVELGNKLAQIPGVWGVYFVLGD
NDFIVMARYKTREEFMEKFLERVMSIPEVERTSAQVVVKIIKESPNIVIF

Ligand information

• Ligand ID: GLN
• InChI: InChI=1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1
• InChIKey: ZDXPYRJPNDTMRX-VKHMYHEASA-N
• SMILES:
  OpenEye OEToolkits 1.5.0: C(CC(=O)N)C(C(=O)O)N
  OpenEye OEToolkits 1.5.0: C(CC(=O)N)[C@@H](C(=O)O)N
  ACDLabs 10.04: O=C(N)CCC(N)C(=O)O
  CACTVS 3.341: N[CH](CCC(N)=O)C(O)=O
  CACTVS 3.341: N[C@@H](CCC(N)=O)C(O)=O
• Formula: C5 H10 N2 O3
• Name: GLUTAMINE
• ChEMBL: CHEMBL930
• DrugBank: DB00130
• ZINC: ZINC000001532526
• PDB chain: 2yx4 Chain A Residue 1001

Receptor-Ligand Complex Structure

Structure summary

• PDB: 2yx4 Crystal structure of glutamine receptor protein from Sulfolobus tokodaii strain 7 in complex with its effector L-glutamine: implications of effector binding in molecular association and DNA binding
• Resolution: 2.0 Å
• Binding residue (original residue number in PDB): K31 S32
• Binding residue (residue number reindexed from 1): K31 S32
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0003677 DNA binding
• GO:0043565 sequence-specific DNA binding

Biological Process

• GO:0043200 response to amino acid

Cellular Component

• GO:0005829 cytosol

External links

• PDB: RCSB:2yx4, PDBe:2yx4, PDBj:2yx4
• PDBsum: 2yx4
• PubMed: 18653535
• UniProt: F9VNT4