Structure of PDB 2yu7 Chain A Binding Site BS01

Receptor Information
>2yu7 Chain A (length=118) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSSGSSGWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSD
QPKAGPGSPLRVTHIKVMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEEA
SGAFVYLRQPYYSGPSSG
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2yu7 Solution structure of the SHP-1 C-terminal SH2 domain complexed with a tyrosine-phosphorylated peptide from NKG2A
ResolutionN/A
Binding residue
(original residue number in PDB)
G15 V44 H64 I65 K66 G77 G78 I97 E98 E99 A100
Binding residue
(residue number reindexed from 1)
G15 V44 H64 I65 K66 G77 G78 I97 E98 E99 A100
Enzymatic activity
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
External links
PDB RCSB:2yu7, PDBe:2yu7, PDBj:2yu7
PDBsum2yu7
PubMed
UniProtP29350|PTN6_HUMAN Tyrosine-protein phosphatase non-receptor type 6 (Gene Name=PTPN6)

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