Structure of PDB 2yu4 Chain A Binding Site BS01

Receptor Information
>2yu4 Chain A (length=94) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSSGSSGFTCPITKEEMKKPVKNKVCGHTYEEDAIVRMIESRQKRKKKAY
CPQIGCSHTDIRKSDLIQDEALRRAIENHNKKRHRHSESGPSSG
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2yu4 Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2yu4 Solution structure of the SP-RING domain in non-SMC element 2 homolog (MMS21, S. cerevisiae)
ResolutionN/A
Binding residue
(original residue number in PDB)		C26 H28 C51 C56
Binding residue
(residue number reindexed from 1)		C26 H28 C51 C56
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.-
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0019789 SUMO transferase activity
Biological Process
GO:0000724 double-strand break repair via homologous recombination
Cellular Component
GO:0030915 Smc5-Smc6 complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2yu4, PDBe:2yu4, PDBj:2yu4
PDBsum2yu4
PubMed
UniProtQ96MF7|NSE2_HUMAN E3 SUMO-protein ligase NSE2 (Gene Name=NSMCE2)

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