Structure of PDB 2yq7 Chain A Binding Site BS01

Receptor Information
>2yq7 Chain A (length=145) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPLGSMSQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRY
RRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALC
VESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYG
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2yq7 Stabilizing the Pro-Apoptotic Bimbh3 Helix (Bimsahb) Does not Necessarily Enhance Affinity or Biological Activity.
Resolution1.901 Å
Binding residue
(original residue number in PDB)		E96 F97 Y101 A104 L108 Q111 E129 D133 N136 G138 R139 V141 Y195
Binding residue
(residue number reindexed from 1)		E45 F46 Y50 A53 L57 Q60 E78 D82 N85 G87 R88 V90 Y144
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:2yq7, PDBe:2yq7, PDBj:2yq7
PDBsum2yq7
PubMed23151250
UniProtQ07817|B2CL1_HUMAN Bcl-2-like protein 1 (Gene Name=BCL2L1)

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