Structure of PDB 2yjy Chain A Binding Site BS01

Receptor Information
>2yjy Chain A (length=337) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRSRLLEDFRNNRYPNLQLREIAGHIMEFSQDQHGSRFIQLKLERATPAE
RQLVFNEILQAAYQLMVDVFGNYVIQKFFEFGSLEQKLALAERIRGHVLS
LALQMYGCRVIQKALEFIPSDQQNEMVRELDGHVLKCVKDQNGNHVVQKC
IECVQPQSLQFIIDAFKGQVFALSTHPYGCRVIQRILEHCLPDQTLPILE
ELHQHTEQLVQDQYGSYVIRHVLEHGRPEDKSKIVAEIRGNVLVLSQHKF
ASNVVEKCVTHASRTERAVLIDEVCTMNDGPHSALYTMMKDQYANYVVQK
MIDVAEPGQRKIVMHKIRPHIATLRKYTYGKHILAKL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2yjy Specific and Modular Binding Code for Cytosine Recognition in Pumilio/Fbf (Puf) RNA-Binding Domains.
Resolution2.598 Å
Binding residue
(original residue number in PDB)
Q860 R864 Q867 F897 N899 Y900 M932 R936 Q939 H972 R1008 Q1011 Q1040 Y1044 R1047 F1077 S1079 N1080 E1083 N1122 Y1123 Y1156 H1159
Binding residue
(residue number reindexed from 1)
Q33 R37 Q40 F70 N72 Y73 M105 R109 Q112 H145 R181 Q184 Q213 Y217 R220 F250 S252 N253 E256 N295 Y296 Y329 H332
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:2yjy, PDBe:2yjy, PDBj:2yjy
PDBsum2yjy
PubMed21653694
UniProtQ14671|PUM1_HUMAN Pumilio homolog 1 (Gene Name=PUM1)

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