Structure of PDB 2ygk Chain A Binding Site BS01

Receptor Information
>2ygk Chain A (length=319) Species: 2287 (Saccharolobus solfataricus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIRKIYDKLVEIKNQIYNIANYLKQEIQDKVNEYWNEYVINHTCKFVAID
GGSFGRPMRIGIVYAVGAESVIGDNKGVKTLSEDGQIGIFKPGNDAQERI
SLLMEALELSLALRDGSKGDYILMDGSLSKKIGNKVDIQQFSDEELKLIR
NVDLNGIISIKDERKMRDLLMLLNQFLVSKIIEEYDGNVLWISKVSRGRD
LFGTDYPDITVLELFTEKRGFSKLIIKNIPEIEVLRKMEYTTFYTRLDNG
KRVIRVDIVGRVDEKIVKEIMDRLSGVSIKGYPFPLLKAHMDVRFSAMDR
EKIIKLVGSKLHKDIEWWP
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain2ygk Chain A Residue 1336 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2ygk Structural and Functional Insights Into DNA-End Processing by the Archaeal Hera Helicase-Nura Nuclease Complex.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		D58 D133
Binding residue
(residue number reindexed from 1)		D50 D125
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0004518 nuclease activity
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:2ygk, PDBe:2ygk, PDBj:2ygk
PDBsum2ygk
PubMed22135300
UniProtQ97WH1|NURA_SACS2 DNA double-strand break repair nuclease NurA (Gene Name=nurA)

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