Structure of PDB 2yds Chain A Binding Site BS01

Receptor Information

>2yds Chain A (length=579) Species: 1502 (Clostridium perfringens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

NQVLVPNLNPTPENLEVVGDGFKITSSINLVGEEEADENAVNALREFLTA
NNIEINSENDPNSTTLIIGEVDDDIPELDEALNGTTAENLKEEGYALVSN
DGKIAIEGKDGDGTFYGVQTFKQLVKESNIPEVNITDYPTVSARGIVEGF
YGTPWTHQDRLDQIKFYGENKLNTYIYAPKDDPYHREKWREPYPESEMQR
MQELINASAENKVDFVFGISPGIDIRFDGDAGEEDFNHLITKAESLYDMG
VRSFAIYWDNIQDKSAAKHAQVLNRFNEEFVKAKGDVKPLITVPTEYDTG
AMVSNGQPRAYTRIFAETVDPSIEVMWTGPGVVTNEIPLSDAQLISGIYD
RNMAVWWNYPVTDYFKGKLALGPMHGLDKGLNQYVDFFTVNPMEHAELSK
ISIHTAADYSWNMDNYDYDKAWNRAIDMLYGDLAEDMKVFANHSTRMDNK
TWAKSGREDAPELRAKMDELWNKLSSKEDASALIEELYGEFARMEEACNN
LKANLPEVALEECSRQLDELITLAQGDKASLDMIVAQLNEDTEAYESAKE
IAQNKLNTALSSFAVISEKVAQSFIQEAL

Ligand information

>2yds Chain T (length=5) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

VPYSS

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2yds Synergy of Peptide and Sugar in O-Glcnacase Substrate Recognition.
Resolution	2.55 Å
Binding residue (original residue number in PDB)	Y189 N298 Y402 W490
Binding residue (residue number reindexed from 1)	Y151 N260 Y364 W452

Enzymatic activity

Enzyme Commision number

3.2.1.169: protein O-GlcNAcase.

External links

PDB	RCSB:2yds, PDBe:2yds, PDBj:2yds
PDBsum	2yds
PubMed	22365600
UniProt	Q0TR53\|OGA_CLOP1 O-GlcNAcase NagJ (Gene Name=nagJ)

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