Structure of PDB 2y4q Chain A Binding Site BS01

Receptor Information
>2y4q Chain A (length=79) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GGSLKKNTVDDISESLRQGGGKLNFDELRQDLKGKGHTDAEIEAIFTKYD
QDGDQELTEHEHQQMRDDLEKEREDLDLD
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2y4q Chain A Residue 800 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2y4q A High-Resolution Structure of the EF-Hand Domain of Human Polycystin-2.
ResolutionN/A
Binding residue
(original residue number in PDB)		D763 D765 D767 E769 E774
Binding residue
(residue number reindexed from 1)		D50 D52 D54 E56 E61
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:2y4q, PDBe:2y4q, PDBj:2y4q
PDBsum2y4q
PubMed24990821
UniProtQ13563|PKD2_HUMAN Polycystin-2 (Gene Name=PKD2)

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