Structure of PDB 2xy8 Chain A Binding Site BS01

Receptor Information
>2xy8 Chain A (length=174) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RQIVLDTETTGMNQIGAHYEGHKIIEIGAVEVVNRRLTGNNFHVYLKPDR
LVDPEAFGVHGIADEFLLDKPTFAEVADEFMDYIRGAELVIHNAAFDIGF
MDYEFSLLKRDIPKTNTFCKVTDSLAVARKMFPGKRNSLDALCARYEIDN
SKRTLHGALLDAQILAEVYLAMTG
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2xy8 Chain A Residue 190 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2xy8 Protein-Protein Haddocking Using Exclusively Pseudocontact Shifts.
ResolutionN/A
Binding residue
(original residue number in PDB)		D12 E14 D167
Binding residue
(residue number reindexed from 1)		D6 E8 D161
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) D12 E14 E61 H162 D167
Catalytic site (residue number reindexed from 1) D6 E8 E55 H156 D161
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006260 DNA replication

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Molecular Function
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Biological Process
External links
PDB RCSB:2xy8, PDBe:2xy8, PDBj:2xy8
PDBsum2xy8
PubMed21626213
UniProtP03007|DPO3E_ECOLI DNA polymerase III subunit epsilon (Gene Name=dnaQ)

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