Structure of PDB 2xxa Chain A Binding Site BS01

Receptor Information
>2xxa Chain A (length=413) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NLTDRLSRTLRNISGRGRLTEDNVKDTLREVRMALLEADVALPVVREFIN
RVKEKAVGHEVNKSLTPGQEFVKIVRNELVAAMGEENQTLNLAAQPPAVV
LMAGLQGAGKTTSVGKLGKFLREKHKKKVLVVSADVYRPAAIKQLETLAE
QVGVDFFPSDVGQKPVDIVNAALKEAKLKFYDVLLVDTAGRLHVDEAMMD
EIKQVHASINPVETLFVVDAMTGQDAANTAKAFNEALPLTGVVLTKVDGD
ARGGAALSIRHITGKPIKFLGVGEKTEALEPFHPDRIASRILGMGDVLSL
IEDIESKVDRAQAEKLASKLKKGDGFDLNDFLEQLRQMKNMGGMASLMGK
DDKVLVRMEAIINSMTMKERAKPEIIKGSRKRRIAAGSGMQVQDVNRLLK
QFDDMQRMMKKMK
Ligand information
>2xxa Chain F (length=102) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcauugcuggugcagcgcagcgcggacgcccgaaccuggucagagccgga
aggcagcagccauaagggaugcuuugcgggugccguugccuuccggcaau
gc
<<<<<<<<<<.<<<<<<<<.<<<<<<<<<<<.....<<<<..<.<<<...
.>>>..>.>>>>...>>>.>>.>>>>>>..>>.>>>>>>...>>>>>>>>
>>
Receptor-Ligand Complex Structure
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PDB2xxa The Crystal Structure of the Signal Recognition Particle in Complex with its Receptor.
Resolution3.94 Å
Binding residue
(original residue number in PDB)		K390 E392 I393 K395 G396 K399 R400
Binding residue
(residue number reindexed from 1)		K372 E374 I375 K377 G378 K381 R382
Enzymatic activity
Enzyme Commision number 3.6.5.4: signal-recognition-particle GTPase.
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0008312 7S RNA binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006612 protein targeting to membrane
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0048500 signal recognition particle
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2xxa, PDBe:2xxa, PDBj:2xxa
PDBsum2xxa
PubMed21330537
UniProtP0AGD7|SRP54_ECOLI Signal recognition particle protein (Gene Name=ffh)

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