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Receptor Information

>2xs1 Chain A (length=697) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

ATFISVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRR
AAVGRPLDKHEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDK
GSLFGGSVKLALASLGYEKSCVLFNCAALASQIAAEQNLDNDEGLKIAAK
HYQFASGAFLHIKETVLSALSREPTVDISPDTVGTLSLIMLAQAQEVFFL
KATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDTLPKEVFPVLAAKHCI
MQANAEYHQSILAKQQYYFGEEIARLQHAAELIKTVASRYDEYVNVKDFS
DKINRALAAAKKDNDFIYHDRVPDLKDLDPIGKATLVKSTPVNVPISQKF
TDLFEKMVPVSVQQSLAAYNQRKADLVNRSIAQMREATTLANGVLASLNL
PAAIEDVSGDTVPQSILTKSRSVIEQGGIQTVDQLIKELPELLQRNREIL
DESLRLLDEEEATDNDLRAKFKERWQRTPSNELYKPLRAEGTNFRTVLDK
AVQADGQVKECYQSHRDTIVLLCKPEPELNAAIPSANPAKTMQGSEVVNV
LKSLLSNLDEVKKEREGLENDLKSVNFDMTSKFLTALAQDGVINEEALSV
TELDRVYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREE
VLKNLATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFAR

>2xs1 Chain B (length=15) Species: 11723 (Simian immunodeficiency virus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

EKPYKEVTEDLLHLN

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2xs1 Identification and Structural Characterization of the Alix-Binding Late Domains of Sivmac239 and Sivagmtan-1.
Resolution	2.296 Å
Binding residue (original residue number in PDB)	K501 A505 D506 V509 N669 E672 G673 F676 I683
Binding residue (residue number reindexed from 1)	K500 A504 D505 V508 N668 E671 G672 F675 I682

Enzyme Commision number

	Biological Process
GO:0071985	multivesicular body sorting pathway

PDB	RCSB:2xs1, PDBe:2xs1, PDBj:2xs1
PDBsum	2xs1
PubMed	20962096
UniProt	Q8WUM4\|PDC6I_HUMAN Programmed cell death 6-interacting protein (Gene Name=PDCD6IP)

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Structure of PDB 2xs1 Chain A Binding Site BS01