Structure of PDB 2x5d Chain A Binding Site BS01

Receptor Information
>2x5d Chain A (length=371) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VFNITAELKMAARRRGEDIIDLSMGNPDGPTPPHIVEKLCTVATSRGIPR
LRRAISHWYRDRYDVQIDPESEAIVTIGSKEGLAHLMLATLDHGDTILVP
NPSYPIHIYGAVIAGAQVRSVPLVPGIDFFNELERAIRESIPKPRMMILG
FPSNPTAQCVELDFFERVVALAKQYDVMVVHDLAYADIVYDGWKAPSIMQ
VPGAKDIAVEFFTLSKSYNMAGWRIGFMVGNPELVSALARIKSYHDYGTF
TPLQVAAIAALEGDQQCVRDIARQYQQRRDVLVKGLREAGWMVENPKASM
YVWAKIPEPYAHLGSLEFAKKLLQDAKVSVSPGIGFGDYGDDHVRFALIE
NRDRLRQAVRGIKAMFRADGL
Ligand information
Ligand IDPLP
InChIInChI=1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14)
InChIKeyNGVDGCNFYWLIFO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341Cc1ncc(CO[P](O)(O)=O)c(C=O)c1O
OpenEye OEToolkits 1.5.0Cc1c(c(c(cn1)COP(=O)(O)O)C=O)O
ACDLabs 10.04O=P(O)(O)OCc1cnc(c(O)c1C=O)C
FormulaC8 H10 N O6 P
NamePYRIDOXAL-5'-PHOSPHATE;
VITAMIN B6 Phosphate
ChEMBLCHEMBL82202
DrugBankDB00114
ZINCZINC000001532514
PDB chain2x5d Chain A Residue 1400 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2x5d The Scottish Structural Proteomics Facility: Targets, Methods and Outputs.
Resolution2.25 Å
Binding residue
(original residue number in PDB)		M43 G44 N45 K244 R373
Binding residue
(residue number reindexed from 1)		M24 G25 N26 K216 R345
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) Y132 D210 A212 K244
Catalytic site (residue number reindexed from 1) Y104 D182 A184 K216
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0009058 biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:2x5d, PDBe:2x5d, PDBj:2x5d
PDBsum2x5d
PubMed20419351
UniProtQ9HV83

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