Structure of PDB 2wuh Chain A Binding Site BS01

Receptor Information
>2wuh Chain A (length=163) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPE
IPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRD
GTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMN
VCMRVELYGCVWL
Ligand information
>2wuh Chain B (length=28) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GPPGPPGPPGPRGQPGVLGFPGPPGPPG
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2wuh Crystallographic Insight Into Collagen Recognition by Discoidin Domain Receptor 2
Resolution1.6 Å
Binding residue
(original residue number in PDB)		D69 H110 I112 E113 L188
Binding residue
(residue number reindexed from 1)		D44 H85 I87 E88 L163
Enzymatic activity
Enzyme Commision number 2.7.10.1: receptor protein-tyrosine kinase.
External links
PDB RCSB:2wuh, PDBe:2wuh, PDBj:2wuh
PDBsum2wuh
PubMed20004161
UniProtQ16832|DDR2_HUMAN Discoidin domain-containing receptor 2 (Gene Name=DDR2)

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