Structure of PDB 2wt7 Chain A Binding Site BS01

Receptor Information
>2wt7 Chain A (length=63) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSALQTEIANLL
KEKEKLEFILAAH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2wt7 Design of a bZIP Transcription Factor with Homo/Heterodimer-Induced DNA-Binding Preference.
Resolution2.3 Å
Binding residue
(original residue number in PDB)
R143 R144 N147 K148 R155 R159
Binding residue
(residue number reindexed from 1)
R6 R7 N10 K11 R18 R22
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:2wt7, PDBe:2wt7, PDBj:2wt7
PDBsum2wt7
PubMed24530283
UniProtP01101|FOS_MOUSE Protein c-Fos (Gene Name=Fos)

[Back to BioLiP]