Structure of PDB 2w69 Chain A Binding Site BS01

Receptor Information
>2w69 Chain A (length=194) Species: 11320 (Influenza A virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AMEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYS
DFHFINEQGESIVVELDDPNALKHRFEIIEGRDRTMAWTVVNSICNTTGA
EKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSTHIHIFSFTG
EEMATKADYTLDEESRARIKTRLFTIRQEMANRGLWDSFRQSER
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain2w69 Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2w69 The CAP-Snatching Endonuclease of Influenza Virus Polymerase Resides in the Pa Subunit
Resolution2.05 Å
Binding residue
(original residue number in PDB)		E80 D108
Binding residue
(residue number reindexed from 1)		E80 D108
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Biological Process
GO:0039694 viral RNA genome replication

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Molecular Function
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Biological Process
External links
PDB RCSB:2w69, PDBe:2w69, PDBj:2w69
PDBsum2w69
PubMed19194459
UniProtP31343|PA_I75A3 Polymerase acidic protein (Gene Name=PA)

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