Structure of PDB 2w0z Chain A Binding Site BS01
Receptor Information
>2w0z Chain A (length=58) Species:
9606
(Homo sapiens) [
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GPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFP
RNYVTAVN
Ligand information
>2w0z Chain B (length=9) Species:
9606
(Homo sapiens) [
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APPPRPPKP
Receptor-Ligand Complex Structure
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PDB
2w0z
Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the Sh3C Domain of Grb2.
Resolution
1.7 Å
Binding residue
(original residue number in PDB)
F7 F9 Q12 E16 D32 W35 P48 N50 Y51
Binding residue
(residue number reindexed from 1)
F9 F11 Q14 E18 D34 W37 P50 N52 Y53
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2w0z
,
PDBe:2w0z
,
PDBj:2w0z
PDBsum
2w0z
PubMed
19523899
UniProt
P62993
|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)
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