Structure of PDB 2vc1 Chain A Binding Site BS01

Receptor Information
>2vc1 Chain A (length=147) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALDDIDRILVRELAADGRATLSELATRAGLSVSAVQSRVRRLESRGVVQG
YSARINPEAVGHLLSAFVAITPLDPSQPDDAPARLEHIEEVESCYSVAGE
ESYVLLVRVASARALEDLLQRIRTTANVRTRSTIILNTFYSDRQHIP
Ligand information
Ligand IDMET
InChIInChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
InChIKeyFFEARJCKVFRZRR-BYPYZUCNSA-N
SMILES
SoftwareSMILES
CACTVS 3.341CSCC[CH](N)C(O)=O
OpenEye OEToolkits 1.5.0CSCCC(C(=O)O)N
CACTVS 3.341CSCC[C@H](N)C(O)=O
OpenEye OEToolkits 1.5.0CSCC[C@@H](C(=O)O)N
ACDLabs 10.04O=C(O)C(N)CCSC
FormulaC5 H11 N O2 S
NameMETHIONINE
ChEMBLCHEMBL42336
DrugBankDB00134
ZINCZINC000001532529
PDB chain2vc1 Chain A Residue 1151 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2vc1 Mechanistic Insights from the Crystal Structures of a Feast/Famine Regulatory Protein from Mycobacterium Tuberculosis H37Rv.
Resolution2.75 Å
Binding residue
(original residue number in PDB)		V100 A101 G102
Binding residue
(residue number reindexed from 1)		V97 A98 G99
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0016597 amino acid binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0043200 response to amino acid
GO:0051260 protein homooligomerization
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2vc1, PDBe:2vc1, PDBj:2vc1
PDBsum2vc1
PubMed17962306
UniProtP96896

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