Structure of PDB 2uwe Chain A Binding Site BS01

Receptor Information
>2uwe Chain A (length=275) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGACVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2uwe Single Mhc Mutation Eliminates Enthalpy Associated with T Cell Receptor Binding.
Resolution2.4 Å
Binding residue
(original residue number in PDB)
Y7 E63 K66 V67 A69 H70 T73 D77 Y84 Y99 Y116 T143 W147 L156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 K66 V67 A69 H70 T73 D77 Y84 Y99 Y116 T143 W147 L156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2uwe, PDBe:2uwe, PDBj:2uwe
PDBsum2uwe
PubMed17825839
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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