Structure of PDB 2rt9 Chain A Binding Site BS01

Receptor Information
>2rt9 Chain A (length=52) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TDEALKPCPRCQSPAKYQPHKKRGLCSRLACGFDFCVLCLCAYHGSEDCR
RG
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2rt9 Chain A Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2rt9 The zinc-binding region (ZBR) fragment of Emi2 can inhibit APC/C by targeting its association with the coactivator Cdc20 and UBE2C-mediated ubiquitylation
ResolutionN/A
Binding residue
(original residue number in PDB)		C573 C576 C591 C596
Binding residue
(residue number reindexed from 1)		C8 C11 C26 C31
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0007088 regulation of mitotic nuclear division
GO:0045835 negative regulation of meiotic nuclear division

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Biological Process
External links
PDB RCSB:2rt9, PDBe:2rt9, PDBj:2rt9
PDBsum2rt9
PubMed25161877
UniProtQ8CDI2|FBX43_MOUSE F-box only protein 43 (Gene Name=Fbxo43)

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