Structure of PDB 2rnw Chain A Binding Site BS01

Receptor Information
>2rnw Chain A (length=118) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHMSKEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVI
RFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCAN
ILEKFFFSKIKEAGLIDK
Ligand information
>2rnw Chain B (length=15) Species: 4932 (Saccharomyces cerevisiae) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ARTKQTARKSTGGKA
Receptor-Ligand Complex Structure
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PDB2rnw Structural Basis of Site-Specific Histone Recognition by the Bromodomains of Human Coactivators PCAF and CBP/p300
ResolutionN/A
Binding residue
(original residue number in PDB)		W746 P747 E750 V752 K753 E756 A757 P758 Y760 N803 E806 S807 E808 Y809
Binding residue
(residue number reindexed from 1)		W32 P33 E36 V38 K39 E42 A43 P44 Y46 N89 E92 S93 E94 Y95
Enzymatic activity
Enzyme Commision number 2.3.1.48: histone acetyltransferase.
2.3.1.57: diamine N-acetyltransferase.
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:2rnw, PDBe:2rnw, PDBj:2rnw
PDBsum2rnw
PubMed18400184
UniProtQ92831|KAT2B_HUMAN Histone acetyltransferase KAT2B (Gene Name=KAT2B)

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