Structure of PDB 2rfx Chain A Binding Site BS01
Receptor Information
>2rfx Chain A (length=275) Species:
9606
(Homo sapiens) [
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GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAP
WIEQEGPEYWDGETRNMKASAQTYRENLRIALRYYNQSEAGSHIIQVMYG
CDVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>2rfx Chain C (length=9) Species:
9606
(Homo sapiens) [
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LSSPVTKSF
Receptor-Ligand Complex Structure
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PDB
2rfx
Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity
Resolution
2.5 Å
Binding residue
(original residue number in PDB)
Y7 E63 N66 M67 T73 N77 Y84 Y99 D114 Y123 T143 K146 W147 V152 Q155 L156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 N66 M67 T73 N77 Y84 Y99 D114 Y123 T143 K146 W147 V152 Q155 L156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2rfx
,
PDBe:2rfx
,
PDBj:2rfx
PDBsum
2rfx
PubMed
18549801
UniProt
P01889
|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)
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