Structure of PDB 2rfm Chain A Binding Site BS01

Receptor Information
>2rfm Chain A (length=183) Species: 50339 (Thermoplasma volcanium) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IVEKIKDEKSINQNLDFLRNYRDSYNRTPLMVACMLGMENAIDKLVENFD
KLEDKDIEGSTALIWAVKNNRLGIAEKLLSKGSNVNTKDFSGKTPLMWSI
IFGYSEMSYFLLEHGANVNDRNLEGETPLIVASKYGRSEIVKKLLELGAD
ISARDLTGLTAEASARIFGRQEVIKIFTEVRRA
Ligand information
Ligand IDBU2
InChIInChI=1S/C4H10O2/c1-4(6)2-3-5/h4-6H,2-3H2,1H3/t4-/m0/s1
InChIKeyPUPZLCDOIYMWBV-BYPYZUCNSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04OCCC(O)C
OpenEye OEToolkits 1.5.0C[C@@H](CCO)O
CACTVS 3.341C[CH](O)CCO
CACTVS 3.341C[C@H](O)CCO
OpenEye OEToolkits 1.5.0CC(CCO)O
FormulaC4 H10 O2
Name1,3-BUTANEDIOL
ChEMBLCHEMBL1231501
DrugBankDB02202
ZINCZINC000001867144
PDB chain2rfm Chain A Residue 195 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2rfm Structural insights into an equilibrium folding intermediate of an archaeal ankyrin repeat protein
Resolution1.65 Å
Binding residue
(original residue number in PDB)		K74 N75
Binding residue
(residue number reindexed from 1)		K68 N69
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
Biological Process
GO:0045944 positive regulation of transcription by RNA polymerase II

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2rfm, PDBe:2rfm, PDBj:2rfm
PDBsum2rfm
PubMed18305166
UniProtQ978J0|Y1425_THEVO Putative ankyrin repeat protein TV1425 (Gene Name=TV1425)

[Back to BioLiP]