Structure of PDB 2rcn Chain A Binding Site BS01

Receptor Information

>2rcn Chain A (length=278) Species: 99287 (Salmonella enterica subsp. enterica serovar Typhimurium str. LT2)

LFGEPAEGIVISRFGMHADVESADGEVHRCNIRRTIRSLVTGDRVVWRPG
KVKGIVEAVHERTSVLTRPVKPIAANIDQIVIVSAILPELSLNIIDRYLV
GCETLQVEPLIVLNKIDLLDDEGMDFVNEQMDIYRNIGYRVLMVSSHTQD
GLKPLEEALTGRISIFAGQSGVGKSSLLNALLGLQNEILTNTAARLYHFP
HGGDVIDSPGVREFGLWHLEPEQITQGFVEFHDYLGHCKYRDCKHDADPG
CAIREAVENGAIAETRFENYHRILESMA

Ligand information

• Ligand ID: ZN
• InChI: InChI=1S/Zn/q+2
• InChIKey: PTFCDOFLOPIGGS-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Zn++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Zn+2]
• Formula: Zn
• Name: ZINC ION
• ChEMBL: CHEMBL1236970
• DrugBank: DB14532
• PDB chain: 2rcn Chain A Residue 359

Receptor-Ligand Complex Structure

Structure summary

• PDB: 2rcn Structure of the ribosomal interacting GTPase YjeQ from the enterobacterial species Salmonella typhimurium.
• Resolution: 2.25 Å
• Binding residue (original residue number in PDB): C305 C310 H312 C318
• Binding residue (residue number reindexed from 1): C238 C243 H245 C251
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 3.6.1.-

Gene Ontology

Molecular Function

• GO:0003924 GTPase activity
• GO:0005525 GTP binding
• GO:0016787 hydrolase activity
• GO:0019843 rRNA binding
• GO:0046872 metal ion binding

Biological Process

• GO:0042254 ribosome biogenesis
• GO:0042274 ribosomal small subunit biogenesis

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:2rcn, PDBe:2rcn, PDBj:2rcn
• PDBsum: 2rcn
• PubMed: 18007041
• UniProt: Q8ZKB0|RSGA_SALTY Small ribosomal subunit biogenesis GTPase RsgA (Gene Name=rsgA)