Structure of PDB 2r05 Chain A Binding Site BS01

Receptor Information
>2r05 Chain A (length=697) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ATFISVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRR
AAVGRPLDKHEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDK
GSLFGGSVKLALASLGYEKSCVLFNCAALASQIAAEQNLDNDEGLKIAAK
HYQFASGAFLHIKETVLSALSREPTVDISPDTVGTLSLIMLAQAQEVFFL
KATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDTLPKEVFPVLAAKHCI
MQANAEYHQSILAKQQYYFGEEIARLQHAAELIKTVASRYDEYVNVKDFS
DKINRALAAAKKDNDFIYHDRVPDLKDLDPIGKATLVKSTPVNVPISQKF
TDLFEKMVPVSVQQSLAAYNQRKADLVNRSIAQMREATTLANGVLASLNL
PAAIEDVSGDTVPQSILTKSRSVIEQGGIQTVDQLIKELPELLQRNREIL
DESLRLLDEEEATDNDLRAKFKERWQRTPSNELYKPLRAEGTNFRTVLDK
AVQADGQVKECYQSHRDTIVLLCKPEPELNAAIPSANPAKTMQGSEVVNV
LKSLLSNLDEVKKEREGLENDLKSVNFDMTSKFLTALAQDGVINEEALSV
TELDRVYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREE
VLKNLATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFAR
Ligand information
>2r05 Chain B (length=11) Species: 362651 (Human immunodeficiency virus type 1 (isolate YU2)) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ELYPLASLRSL
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2r05 Structural and functional studies of ALIX interactions with YPX(n)L late domains of HIV-1 and EIAV.
Resolution2.55 Å
Binding residue
(original residue number in PDB)		A505 D506 N669 E672 G673 F676 L680
Binding residue
(residue number reindexed from 1)		A504 D505 N668 E671 G672 F675 L679
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0071985 multivesicular body sorting pathway

View graph for
Biological Process
External links
PDB RCSB:2r05, PDBe:2r05, PDBj:2r05
PDBsum2r05
PubMed18066081
UniProtQ8WUM4|PDC6I_HUMAN Programmed cell death 6-interacting protein (Gene Name=PDCD6IP)

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