BioLiP

Receptor Information

>2r03 Chain A (length=697) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

ATFISVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRR
AAVGRPLDKHEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDK
GSLFGGSVKLALASLGYEKSCVLFNCAALASQIAAEQNLDNDEGLKIAAK
HYQFASGAFLHIKETVLSALSREPTVDISPDTVGTLSLIMLAQAQEVFFL
KATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDTLPKEVFPVLAAKHCI
MQANAEYHQSILAKQQYYFGEEIARLQHAAELIKTVASRYDEYVNVKDFS
DKINRALAAAKKDNDFIYHDRVPDLKDLDPIGKATLVKSTPVNVPISQKF
TDLFEKMVPVSVQQSLAAYNQRKADLVNRSIAQMREATTLANGVLASLNL
PAAIEDVSGDTVPQSILTKSRSVIEQGGIQTVDQLIKELPELLQRNREIL
DESLRLLDEEEATDNDLRAKFKERWQRTPSNELYKPLRAEGTNFRTVLDK
AVQADGQVKECYQSHRDTIVLLCKPEPELNAAIPSANPAKTMQGSEVVNV
LKSLLSNLDEVKKEREGLENDLKSVNFDMTSKFLTALAQDGVINEEALSV
TELDRVYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREE
VLKNLATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFAR

>2r03 Chain B (length=8) Species: 11672 (Equine infectious anemia virus (ISOLATE WYOMING)) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

NLYPDLSE

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2r03 Structural and functional studies of ALIX interactions with YPX(n)L late domains of HIV-1 and EIAV.
Resolution	2.59 Å
Binding residue (original residue number in PDB)	A505 D506 E672 G673 F676
Binding residue (residue number reindexed from 1)	A504 D505 E671 G672 F675

Enzyme Commision number

	Biological Process
GO:0071985	multivesicular body sorting pathway

PDB	RCSB:2r03, PDBe:2r03, PDBj:2r03
PDBsum	2r03
PubMed	18066081
UniProt	Q8WUM4\|PDC6I_HUMAN Programmed cell death 6-interacting protein (Gene Name=PDCD6IP)

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Structure of PDB 2r03 Chain A Binding Site BS01