Structure of PDB 2qzo Chain A Binding Site BS01
Receptor Information
>2qzo Chain A (length=228) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVLEE
KDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKG
MEHLYSMKCKNVVPLSDLLLEMLDAHRL
Ligand information
>2qzo Chain C (length=9) Species:
10090
(Mus musculus) [
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HKILHRLLQ
Receptor-Ligand Complex Structure
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PDB
2qzo
Coupling of receptor conformation and ligand orientation determine graded activity.
Resolution
1.72 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 Q375 V376 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I54 K58 L68 Q71 V72 E76 D217 L218 E221
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2qzo
,
PDBe:2qzo
,
PDBj:2qzo
PDBsum
2qzo
PubMed
20924370
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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