Structure of PDB 2qxv Chain A Binding Site BS01

Receptor Information
>2qxv Chain A (length=352) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGE
IRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQ
CIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGG
VEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYN
FISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMED
DIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYV
WDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWD
RL
Ligand information
>2qxv Chain B (length=29) Species: 10090 (Mus musculus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
TMFSSNRQKILERTETLNQEWKQRRIQPV
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2qxv Structural basis of EZH2 recognition by EED
Resolution1.82 Å
Binding residue
(original residue number in PDB)		W102 S104 E106 D108 V111 L134 Y153 S158 P160 R200 L245 L307 G308 D309 L310 F364 W365 Q366 L383 V385 E386 R412
Binding residue
(residue number reindexed from 1)		W22 S24 E26 D28 V31 L54 Y73 S78 P80 R120 L165 L227 G228 D229 L230 F284 W285 Q286 L303 V305 E306 R332
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2qxv, PDBe:2qxv, PDBj:2qxv
PDBsum2qxv
PubMed17937919
UniProtQ921E6|EED_MOUSE Polycomb protein EED (Gene Name=Eed)

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