Structure of PDB 2qxm Chain A Binding Site BS01
Receptor Information
>2qxm Chain A (length=233) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYRPFSEASMMGLLTNLADRELVHM
INWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPN
LLLDRNEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFL
KSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRH
MSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL
Ligand information
>2qxm Chain C (length=11) Species:
10090
(Mus musculus) [
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HKILHRLLQDS
Receptor-Ligand Complex Structure
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PDB
2qxm
NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I51 K55 L65 V69 D222 L223 E226
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2qxm
,
PDBe:2qxm
,
PDBj:2qxm
PDBsum
2qxm
PubMed
18344977
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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