Structure of PDB 2qqs Chain A Binding Site BS01

Receptor Information
>2qqs Chain A (length=109) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QSITAGQKVISKHKNGRFYQCEVVRLTTETFYEVNFDDGSFSDNLYPEDI
VSQDCLQFGPPAEGEVVQVRWTDGQVYGAKFVASHPIQMYQVEFEDGSQL
VVKRDDVYT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2qqs Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor.
Resolution2.82 Å
Binding residue
(original residue number in PDB)		E959 E961
Binding residue
(residue number reindexed from 1)		E63 E65
Enzymatic activity
Enzyme Commision number 1.14.11.66: [histone H3]-trimethyl-L-lysine(9) demethylase.
1.14.11.69: [histone H3]-trimethyl-L-lysine(36) demethylase.
External links
PDB RCSB:2qqs, PDBe:2qqs, PDBj:2qqs
PDBsum2qqs
PubMed18084306
UniProtO75164|KDM4A_HUMAN Lysine-specific demethylase 4A (Gene Name=KDM4A)

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