Structure of PDB 2qqo Chain A Binding Site BS01

Receptor Information
>2qqo Chain A (length=431) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE
HDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAV
AKDGFSARYYLVHQCNVPLGMESGRIANEQISASSTYSDGRWTPQQSRLH
GDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKSYK
LEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTRFVRIRPQ
TWHSGIALRLELFGCRVTDAPCSNMLGMLSGLIADSQISASSTQEYLWSP
SAARLVSSRSGWFPRIPQAQPGEEWLQVDLGTPKTVKGVIIQGARGGITA
VEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPKLFEGNMHYDTPDIRRFD
PIPAQYVRVYPERWSPAGIGMRLEVLGCDWT
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2qqo Chain A Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2qqo Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding
Resolution2.3 Å
Binding residue
(original residue number in PDB)		E197 D211 D252 A254 V255
Binding residue
(residue number reindexed from 1)		E50 D56 D97 A99 V100
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2qqo, PDBe:2qqo, PDBj:2qqo
PDBsum2qqo
PubMed17989695
UniProtO60462|NRP2_HUMAN Neuropilin-2 (Gene Name=NRP2)

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