Structure of PDB 2qlx Chain A Binding Site BS01

Receptor Information
>2qlx Chain A (length=108) Species: 386 (Rhizobium leguminosarum bv. trifolii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GDMTLEKHAFKMQLNPGMEAEYRKRHDEIWPELVDLLHQSGASDYSIHLD
RETNTLFGVLTRPKDHTMASLPDHPVMKKWWAHMADIMATNPDNSPVQSD
LVTLFHMP
Ligand information
Ligand IDRM4
InChIInChI=1S/C6H12O5/c1-2-3(7)4(8)5(9)6(10)11-2/h2-10H,1H3/t2-,3-,4+,5+,6-/m0/s1
InChIKeySHZGCJCMOBCMKK-YJRYQGEOSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C[C@H]1[C@@H]([C@H]([C@H]([C@H](O1)O)O)O)O
CACTVS 3.341C[C@@H]1O[C@H](O)[C@H](O)[C@H](O)[C@H]1O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)C
OpenEye OEToolkits 1.5.0CC1C(C(C(C(O1)O)O)O)O
CACTVS 3.341C[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
FormulaC6 H12 O5
Namebeta-L-rhamnopyranose;
beta-L-rhamnose;
6-deoxy-beta-L-mannopyranose;
L-rhamnose;
rhamnose
ChEMBL
DrugBank
ZINCZINC000003861281
PDB chain2qlx Chain A Residue 300 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2qlx RhaU of Rhizobium leguminosarum is a rhamnose mutarotase.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		M10 Y20 H24 Y43 W78 W79
Binding residue
(residue number reindexed from 1)		M12 Y22 H26 Y45 W80 W81
Annotation score5
Enzymatic activity
Enzyme Commision number 5.1.3.32: L-rhamnose mutarotase.
Gene Ontology
Molecular Function
GO:0016853 isomerase activity
GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives
GO:0062192 L-rhamnose mutarotase activity
Biological Process
GO:0019299 rhamnose metabolic process
GO:0019301 rhamnose catabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2qlx, PDBe:2qlx, PDBj:2qlx
PDBsum2qlx
PubMed18156270
UniProtQ7BSH1|RHAM_RHILT L-rhamnose mutarotase (Gene Name=rhaM)

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