Structure of PDB 2qh6 Chain A Binding Site BS01
Receptor Information
>2qh6 Chain A (length=232) Species:
9606
(Homo sapiens) [
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NSLALSLTADQMVSALLDAEPPILYSEYDRPFSEASMMGLLTNLADRELV
HMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLN
SGVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIR
HMSNKGMEHLYSMKCKNVPLSDLLLEMLDAHR
Ligand information
>2qh6 Chain C (length=10) Species:
10090
(Mus musculus) [
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HKILHRLLQD
Receptor-Ligand Complex Structure
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PDB
2qh6
NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Resolution
2.7 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 L379 E380 L539 E542
Binding residue
(residue number reindexed from 1)
I53 K57 L67 L74 E75 L223 E226
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2qh6
,
PDBe:2qh6
,
PDBj:2qh6
PDBsum
2qh6
PubMed
18344977
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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