Structure of PDB 2qgw Chain A Binding Site BS01

Receptor Information
>2qgw Chain A (length=236) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILS
HIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2qgw NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Resolution2.39 Å
Binding residue
(original residue number in PDB)
I358 L372 E542 M543
Binding residue
(residue number reindexed from 1)
I54 L68 E230 M231
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2qgw, PDBe:2qgw, PDBj:2qgw
PDBsum2qgw
PubMed18344977
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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