Structure of PDB 2qab Chain A Binding Site BS01
Receptor Information
>2qab Chain A (length=236) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILS
HIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>2qab Chain C (length=11) Species:
10090
(Mus musculus) [
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KHKILHRLLQD
Receptor-Ligand Complex Structure
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PDB
2qab
NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Resolution
1.89 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I54 K58 L68 D226 L227 E230
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2qab
,
PDBe:2qab
,
PDBj:2qab
PDBsum
2qab
PubMed
18344977
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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