Structure of PDB 2qa6 Chain A Binding Site BS01

Receptor Information
>2qa6 Chain A (length=243) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLALSLTADQMVSALLDAEPPILYSEYDRPFSEASMMGLLTNLADRELVH
MINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAP
NLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNS
GVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQ
LLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2qa6 NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Resolution2.6 Å
Binding residue
(original residue number in PDB)
I358 K362 V376 L379 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I52 K56 V70 L73 D232 L233 E236
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2qa6, PDBe:2qa6, PDBj:2qa6
PDBsum2qa6
PubMed18344977
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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